Pedigree-drawing with R and graphviz

Bioinformatics Advance Access originally published online on February 17, 2006
Bioinformatics 2006 22(8):1013-1014; doi:10.1093/bioinformatics/btl058

Jing Hua Zhao

MRC Epidemiology Unit, Strangeways Research Laboratory Cambridge CB1 8RN, UK

Summary: Two functions for pedigree-drawing available in R (http://www.r-project.org): plot.pedigree in kinship and pedtodot in gap are described. The latter requires graphviz (http://www.graphviz.org). They can produce many pedigree diagrams quickly into a single file, serving as alternatives to programs that only offer interactive use.

Availability: Packages kinship and gap are available from http://cran.r-project.org.

Contact: jinghua.zhao@mrc-epid.cam.ac.uk

Group meeting recap [4.7.2006]

0) We need to looking to machine learning literature to find current discussion/proposals on comparing different methods' performance.

1) Attached is the memo contains brief description of the data and info on the workshop in general.

2) The nature (2004) paper for problem 1:
Genetic analysis of genome-wide variation in human gene expression


Another related 2005 paper:
Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease


A PLoS genetics (2005) paper:
Genome-Wide Associations of Gene Expression Variation in Humans


3) OMIM on RHEUMATOID ARTHRITIS for problem 2:
[most important papers on this disorder is linked there too]

GAW15_data_memo_FINAL.pdf